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COMPLEMENT C2A
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DeCS
Descriptor
English
:
Complement C2a
Descriptor
Spanish
:
Complemento C2a
Descriptor
Portuguese
:
Complemento C2a
Tree Number:
D12.776.124.486.274.150.500
Definition
English
:
The COOH-terminal fragment of COMPLEMENT 2, released by the action of activated
COMPLEMENT C1S
. It is a
SERINE
PROTEASE. C2a combines with
COMPLEMENT C4B
to form C4b2a (CLASSICAL PATHWAY
C3 CONVERTASE
) and subsequent C4b2a3b (CLASSICAL PATHWAY C5 CONVERTASE).
Pharmacological Action:
Immunologic Factors
History Note
English
:
2006 (1986)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
50825
Unique Identifier:
D050678
Occurrence in VHL
:
Similar:
DeCS
CID-10
SciELO
LILACS
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